WHISCON
World Health Information Science Consultants, LLC
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Consultants
WHISCON Consultants are widely published academic researchers trained in medicine, biostatistics and epidemiology.   Each has directed substantive investigations, has advanced analytic methodology and has been committed to professional service.
Alan Brookhart, PhD is an Assistant Professor of Medicine at Harvard Medical School and a Biostatistician in the Division of Pharmacoepidemiology and Pharmacoeconomics at Brigham and Women's Hospital.  His research focuses on the development and application of statistical methods for drug utilization and outcomes research using large, health care claims data files.  Areas of particular interest include the use of instrumental variable methods to assess short-term drug exposure effects, model selection strategies for efficient control of confounding, and multilevel analysis of prescription drug use data.  He is an active member of International Society for Pharmacoepidemiology and editorial board member of Pharmacoepidemiology and Drug Safety. Dr. Brookhart received his PhD in Biostatistics from the University of California at Berkeley, where his thesis involved development of model selection methods for marginal structural models. his thesis involved development of model selection methods for marginal structural models. his thesis involved development of model selection methods for marginal structural models.


Sonia Hernández-Díaz, MD, DrPH is the Director of the Pharmacoepidemiology Program at the Harvard School of Public Health, where she is an Assistant Professor in the Department of Epidemiology.  Dr. Hernández-Díaz investigates patterns of drug use and drug safety during pregnancy and has special interest in the safety of anti-inflammatory drugs.  With many contributions to the study of nutrition, infection and child development in disadvantaged societies, Dr. Hernández-Díaz is also a leader in the application of innovative methodologic concepts, including the use of causal structural approaches to define confounding and selection biases that might facilitate the identification, communication, and resolution of common analytical problems.  Dr. Hernández-Díaz graduated from the Madrid Autonomous University School of Medicine and received her doctorate degree in Public Health from Harvard.

Tobias Kurth, MD, ScD
 is Director of Research at INSERM Unit 708 – Neuroepidemiology, Bordeaux, France, Co-Director of Neuroepidemiology in the Division of Preventive Medicine, Brigham Women’s Hospital, Harvard Medical School, Boston, MA, where he is Lecturer in Medicine.  He is also an Assistant Professor of Epidemiology at the Harvard School of Public Health.  His research encompasses on the interrelationships between vascular risk factors, neurological diseases and cardiovascular disease as well as the evaluation of risks and benefits of medication use and epidemiologic methods, in particular the application of tools to control for confounding in observational studies.  Dr. Kurth received his M.D. from the University of Tübingen, Germany and his doctorate in epidemiology with concentration in pharmacoepidemiology from the Harvard School of Public Health. Dr. Kurth has published >150 articles in indexed journals and is ranked among the top 1% of scientists by the ISI Web of Science in the field clinical medicine.

Sebastian Schneeweiss, MD, ScD
, is Vice Chief of the Division of Pharmacoepidemiology and Pharmacoeconomics Brigham and Women’s Hospital  in Boston, where he is also Principal Investigator of the DEcIDE Research Center on Comparative Effectiveness Research.  He is an Associate Professor of Medicine at the Harvard Medical School and of Epidemiology at the Harvard School of Public Health.  Dr. Schneeweiss’s research focuses on the comparative safety and effectiveness of biopharmaceuticals, analytic methods to improve the validity of epidemiologic studies using large claims databases, and longitudinal data analyses to evaluate risk management programs and drug reimbursement policies.   Dr. Schneeweiss is a general internist with a doctorate in epidemiology from Harvard.  He is Chair of the Education Committee of the International Society for Pharmacoepidemiology and Chair of the Pharmacoepidemiology Section of the American Society of Clinical Pharmacology and Therapeutics.


John Seeger, PharmD, DrPH, is an epidemiologist in the Division of Pharmacoepidemiology and Pharmacoeconomics at Brigham and Women’s Hospital in Boston and Lecturer at Harvard Medical School.  He is extensively involved in the DEcIDE Research Center on Comparative Effectiveness Research and is a co-instructor for two courses in Epidemiology at the Harvard School of Public Health.  Dr. Seeger has conducted dozens of studies that have addressed regulatory drug safety issues across a wide range of drugs and disease conditions.  Most of this work has involved the use of health insurance claims databases as platforms for pharmacoepidemiology, so Dr. Seeger's methodologic expertise focuses on research issues encountered in such settings.  He has worked extensively with propensity scores and related methods that seek to mitigate confounding by collapsing covariates.  He has authored or co-authored dozens of articles in the peer-reviewed medical literature. Dr. Seeger is a clinical pharmacist with a doctorate in epidemiology from Harvard’s School of Public Health, and is active in the International Society for Pharmacoepidemiology.
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